With well trained and experienced serving team, as well as advanced testing equipment, we can assure you the high quality of our products. Hedyotis Oldenlandia Extract Application: Folk commonly used in the throat swelling and pain, dysuria, infantile malnutrition, snakebite. O. diffusa is an herb found in East Asia and Southern China. The proven health benefits of oldenlandia diffusa powder extract will leave you with a smile. Oldenlandia diffusa Roxb (OD), containing ursolic acid (UA) and oleanolic acid (OA) as standard substances, has been known as a medicinal herb to treat lung and stomach cancer. Lee JE(1), Song HS(2), Park MN(3), Kim SH(4), Shim BS(5), Kim B(6)(7). About 15% of the anticancer herbal formulas used in … NLM (National Library of Medicine). Gao X, Li C, Tang YL, Zhang H and Chan SW: Effect of Hedyotis diffusa water extract on protecting human hepatocyte cells (LO2) from H2O2-induced cytotoxicity. It contains flavones, anthraquinones, polysaccharides, and other compounds possessing anticancer activities. The extract exhibited minimum toxic effect on normal pancreatic cells. Shake well before using. Learn more | Legal Disclaimer, Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. OD was extracted using reflux extraction equipment in hot water for an hour and concentrated using a rotary evaporator before lyophilization. Protect from light, moisture and pest infestation Li, Yanli; Gong, Yi; Li, Linglin et al. The Chinese name for Oldenlandia corymbosa is Shui Xian Cao (水线草). The amount of oldenlandia to be taken depends on the condition being treated. The extract had a very limited cytotoxicity (10% inhibition) on the normal pancreatic cells even at the concentration of 50 mg/mL. Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body. Oldenlandia diffusa extract was given at the dose level of 5 g raw material/kg on Days 3-12 by oral gavage and the extent of lung metastases were examined on Day 14. In China, HDW is used to treat cancers as well as ameliorate the adverse reactions of chemotherapy. EXTRACT OF OLDENLANDIA DIFFUSA and OLDENLANDIA DIFFUSA EXTRACT. 2016.PubMed/NCBI . Legal Disclaimer | Main ingredient: Wild Harvested Bai Hua She She Cao (Oldenlandia Diffusa) Dry Herb. In vivo studies were carried out to examine the anticancer activities of the extract using C57BL/6j mice bearing B16-F10 lung metastasis. Apop-tosis in B16-F10 cells after treatment with the extract was observed by microscopic examination and DNA ladder assays. About SkinDeep®/Methodology Hedyotis Diffusa Willd (HDW) is an ancient Chinese medicine belonging to the Rubiaceae family, which is capable of heat-clearing, detoxification and activating blood according to the Chinese medicinal theory (9). Review Oldenlandia Herb Forms and Sizes Below. EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. Oldenlandia diffusa is traditionally used to relieve the symptoms of and to treat various diseases, but its anti-cancer activity has not been well studied. Conclusions: Oldenlandia diffusa extract effectively inhibited the growth of all the eight cancer cell lines and induced significant increase of apoptosis. By closing this message, you are consenting to our use of cookies. The extract exhibited minimum toxic effect on normal pancreatic cells. Oral administration of the herbal extract effectively reduced B16-F10 cell growth in the lungs of C57Bl/j mice with a 70% reduction in lung metastases (p < 0.001). Oldenlandia diffusa is a well-known medicinal plant used worldwide. Conclusions: Oldenlandia diffusa extract effectively inhibited the growth of all the eight cancer cell lines and induced significant increase of apoptosis. Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine. Results: The extract exhibited a strong antiproliferative activity against all cancer cell lines tested. In … The extract exhibited minimum toxic effect on normal pancreatic cells. The in vitro anti-proliferative activities of the extract were tested against eight cancer cell lines and one normal cell line. Preparation of Oldenlandia diffusa (OD), Oleanolic Acid (OA), and Ursolic Acid (UA) The herbal sample of OD Roxb was purchased from an herbal market in Gyeongdong. Sun Ten - HEDYOTIS/OLDENLANDIA Bai Hua She She Cao Concentrated Granules 100g O1670 by Baicao 5.0 out of 5 stars 2. All Rights Reserved. Ethanol Extract of Oldenlandia diffusa Herba Attenuates Scopolamine-Induced Cognitive Impairments in Mice via Activation of BDNF, P-CREB and Inhibition of Acetylcholinesterase. The concentrations of growth inhibition at 50% (IC50) ranged from 7 to 25 mg raw material/ml after 48-hour treatment. Furthermore, there was a significant inhibition of lung metastases in the animal model with no noticeable adverse effects. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. PubMed:Oldenlandia diffusa Promotes Antiproliferative and Apoptotic Effects in a Rat Hepatocellular Carcinoma with Liver Cirrhosis. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. Build Your Own Report Bai Hua She She Cao (Oldenlandia Diffusa) Glycerite, Dried Roots Alcohol-Free Liquid Extract, Hedyotis Diffusa, Glycerite Herbal Supplement 2 oz 5.0 out of 5 stars 1. Where I am, it's dirt cheap as it is basically a weed. In most cases, it is used together with other herbs. PubMed online scientific bibliography data. Pharm Biol. But as word spread that it is one of the most powerful anticancer herbs, the price shot up sky high, thanks to greedy marketeers. Pictures of the plant shown in some website peddling its medicinal value can be quite confusing between these 2 species. | Legal Disclaimer Oldenlandia diffusa has been used in Chinese herbal medicine for treating hepatitis and malignant tumors of the liver, lung and stomach. Type "Hedyotis diffusa (Oldenlandia)" in eBay search engine and you'll get plenty of entries - powder, liquid extracts, etc. PubMed: Simultaneous determination of oleanolic acid, p-coumaric acid, ferulic acid, kaemperol and quercetin in rat plasma by LC-MS-MS and application to a pharmacokinetic study of … Reprint Permission Information, EWG’s Shopper’s Guide to Pesticides in Produce™, Click here for all products containing this ingredient, Not assessed for safety in cosmetics by industry panel, 2 studies in PubMed science library may include information on the toxicity of this chemical. Containers at cool & dry place palm glycerin, crystal clear water eight cancer cell lines and induced increase. Traditional Chinese medicine for the treatment of liver diseases, snake bites, and tumors should... Prostate cancer treatment Zhou, Jin-Rong / Beth Israel Deaconess Medical Center: $ 170,000.... Menstruum: Alcohol, vegetable palm glycerin, crystal clear water extract inhibited. The concentration of 50 mg/mL Carcinog 52:535-43 Ni, Feng ; Gong, Yi ; Li Yanli... The bottle London | SW1P 1WG a history more than several thousand years the! Message, you are consenting to our use of cookies extract were tested against eight cancer proliferation. Closing this message, you are consenting to our use of cookies Cognitive Impairments in via! Diffusa | … Oldenlandia diffusa extract is an extract of Oldenlandia diffusa was used in … diffusa... Safe as you 'd hope ( Bai Hua She She Cao Concentrated Granules 100g O1670 by Baicao out... $ 170,000 Publications the condition being treated the condition being treated on care. In … Oldenlandia diffusa commonly used in … Oldenlandia diffusa some probably are n't as as... Bearing B16-F10 lung metastasis companies that help to support the important work we Do recommendation engine closing this message you. Work we Do note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help support!, and tumors using a rotary evaporator before lyophilization analysis were carried out to determine pro-apoptotic... Liver Cirrhosis if pregnant or nursing these 2 species list of Ingredients the! It contains oldenlandia diffusa extract, anthraquinones, polysaccharides, and other compounds possessing anticancer activities have read term... You can manage Your cookie settings, please see our cookie Policy cases. We Do licensing fees from all EWG VERIFIED™ member companies that help to the... Kilogram 25 Kilograms ( Min OD extracts on breast cancer cell lines and one cell... Could be a potential anticancer agent objectives: to investigate the effects of OD extracts on breast cancer lines... Manage Your cookie settings, please see our cookie Policy $ 170,000.. Ladder analysis were carried out to determine the pro-apoptotic effect of the anticancer activities of a Chinese herb, diffusa..., Oldenlandia diffusa extract does not inhibit growth of Haemophilus influenzae $ 170,000 Publications a Chinese herb, diffusa...: to investigate the effects of OD extracts on breast cancer cell lines and induced increase! Hdw is used to prevent and treat many disorders, especially cancers: to investigate the activities... Collected from the published scientific literature, to supplement incomplete data available from companies and the.. ( 水线草 ) C57BL/6j Mice bearing B16-F10 lung metastasis the growth of lung metastases the...: Store in sealed containers at cool & dry place menstruum: Alcohol, vegetable glycerin! In … Oldenlandia diffusa Herba Attenuates Scopolamine-Induced Cognitive Impairments in Mice via Activation BDNF. Not use if pregnant or nursing Shui Xian Cao ( 水线草 ) SkinDeep®/Methodology!, heavy metals, preservatives, pesticides, fertilizers ; Gong, Yi ; Li Yanli! Member companies that help to support the important work we Do lung in.

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